Abstract
Diabetes is considered to be a risk factor equivalent of pre-existing coronary heart disease for the development of future myocardial infarction and cardiovascular death. In addition to improved glucose control, the increased risk of coronary disease in diabetics makes intensive lipid-lowering treatment necessary. A number of studies have demonstrated that lipid-lowering therapy in diabetes is effective in decreasing the number of cardiac events. The most important objective in the treatment of diabetes is to reduce LDL-C to a target of <100 mg/dl. Different types of lipid-lowering drugs are available. Statins are the current lipid-lowering drugs of choice to reduce LDL-C. However, some questions remain unanswered. This article will describe and discuss the significance of LDL-C lowering therapy in subjects with diabetes.
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