Abstract
Bladder Signet-Ring Cell Carcinoma (SRCC) is extremely rare. It is most often primary, but metastatic disease is described in a few cases in literature. Herein we describe a case of primary SRCC of the stomach with metastasis to the bladder that did not have the chance to receive treatment and passed away due to tumor aggressiveness. We also reviewed the literature and discussed the etiology, prognosis and treatment of bladder SRCC.
Highlights
Bladder Signet-Ring Cell Carcinoma (SRCC) is extremely rare, representing a maximum of 2% of all bladder cancers [1,2]. It is most often primary, but metastatic disease is described in a few cases in literature
Due to low response to chemotherapy and radiotherapy, this is a cancer of poor prognosis [2]
We describe a case of primary SRCC of the stomach with metastasis to the bladder that did not have the chance to receive treatment and passed away due to tumor aggressiveness
Summary
Bladder Signet-Ring Cell Carcinoma (SRCC) is extremely rare, representing a maximum of 2% of all bladder cancers [1,2]. It is most often primary, but metastatic disease is described in a few cases in literature. The survey showed an infiltrative lesion in the right lateral wall of the bladder. A gastric ulcer biopsy performed during endoscopy confirmed diagnosis of poorly differentiated adenocarcinoma, diffuse-type with signet ring cells, according to the Laurenn Classification. The comparative abdominal CT performed 29 days after the arrival (Figure 2) showed increased infiltrative lesion in the right lateral wall of the bladder with involvement of the distal ureter. In spite of full treatment there was refractory shock, she passed away
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