Abstract

Sickle Cell Anemia is one diagnosis under a larger umbrella of hemoglobinopathy diseases known as Sickle Cell Disease. In this review, we will evaluate not just curative measures toward Sickle Cell Anemia, but also the potential for stem cell transplantation with respect to Sickle Cell Disease. The goal of this review article is to examine the current treatment options available for patients with Sickle Cell Anemia and the potential use of stem cell therapy as a cure. This team of authors considers the benefits and disadvantages associated with various aspects of stem cell transplantation including types of stem cell transplantations, patient age, pre and post-transplantation care, genetic variations in stem cells, and areas of future research. Stem cell therapy is an important development to aid patients suffering from Sickle Cell Disease, but access to donors, patient safety, ethical considerations, and accessibility of treatment need further evaluation for it to become the clinical standard of care.

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