Abstract
One-anastomosis gastric bypass is a promising type of bariatric surgery, but it may lead to a deficiency in important nutrients, such as fatty acids. The short-term effects of one-anastomosis gastric bypass on serum fatty acids have not been studied thus far. Therefore, the aim of this study was to determine the effect of one-anastomosis gastric bypass on serum fatty acid composition two weeks after surgery. This study included 38 patients who underwent one-anastomosis gastric bypass as surgical treatment for morbid obesity. Serum fatty acid composition was analyzed before and two weeks after surgery using gas chromatography–mass spectrometry. We observed a decrease in essential polyunsaturated fatty acids (p < 0.001 for linolenic acid and p < 0.001 for linoleic acid) and odd-chain fatty acids (p = 0.004) in the serum of obese patients shortly after a one-anastomosis gastric bypass. Considering the benefits of the aforementioned fatty acids for human health, the implementation of a fatty-acid-rich diet or the use of supplementation may be recommended for patients immediately after one-anastomosis gastric bypass.
Highlights
Bariatric surgery (BS) is currently the most effective method for obesity treatment [1].some studies demonstrated negative BS effects, such as limited nutrient uptake, hypoglycemia, and osteoporosis [1]
Obese subjects demonstrated severely disturbed serum Fatty acids (FAs) composition compared to the control subjects
This included a decrease in branched-chain saturated FAs (BCFAs) and an increase in monounsaturated FAs (MUFAs) (Table 2)
Summary
Bariatric surgery (BS) is currently the most effective method for obesity treatment [1].some studies demonstrated negative BS effects, such as limited nutrient uptake, hypoglycemia, and osteoporosis [1]. The status of BS as a weight-reduction treatment is evolving to reflect its potential use as a treatment for metabolic disorders. It is worth focusing on patient comfort and health in the postsurgical period, when the body is weak and requires nutritional support. Some FAs, despite existing in small quantities, play an important role in the human body. Examples of such FAs are omega-3 polyunsaturated FAs (n-3 PUFAs), which have anti-inflammatory properties, branched-chain saturated FAs (BCFAs), which were shown to Nutrients 2020, 12, 187; doi:10.3390/nu12010187 www.mdpi.com/journal/nutrients
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