Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study)

Arctic Research Team Arctic Research Team,Brian Cuthbertson,Deborah White,Esther Daubney,Gema Milla,Iain Robert Louis Kean,John A Clark,John Myburgh,John Pappachan,Julian Parkhill,Kathy Rowan,Nazima Pathan,Nigel Klein,Paloma Ferrando-Vivas,Paul Mouncey,Stephen Baker,Theodore Gouliouris,Zhenguang Zhang

doi:10.1136/gutjnl-2023-330851

Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study)

Arctic Research Team Arctic Research Team, Brian Cuthbertson + Show 16 more

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https://doi.org/10.1136/gutjnl-2023-330851

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Journal: Gut	Publication Date: Jan 22, 2024
Citations: 1	License type: CC BY 4.0

Affiliation: Sunnybrook Hospital, University of Cambridge, University College London

#Antimicrobial Resistance Gene #End Of Mechanical Ventilation #Standard Antimicrobial Therapy #Antimicrobial Resistance Profiles #Altered Gut Microbiota #Mechanical Ventilation #Infection Control #Antimicrobial Resistance #Microbiome Profiles #Standard Care

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ObjectiveSelective decontamination of the digestive tract (SDD) is a well-studied but hotly contested medical intervention of enhanced infection control. Here, we aim to characterise the changes to the microbiome and...

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Short-duration selective decontamination of the digestive tract infection control does not contribute to increased antimicrobial resistance burden in a pilot cluster randomised trial (the ARCTIC Study)