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https://doi.org/10.1016/j.tet.2006.02.056
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Cite Journal: Tetrahedron |  Publication Date: Mar 10, 2006 |
 Citations: 10 |
Herein, we describe short and efficient syntheses of isoxazole-3-carboxylic acid 3a and imino-oxopentanoic acid 8 achiral precursors of 4-hydroxyisoleucine. The developed procedures involve readily available and cheap starting materials and can easily be transposed to the large scale.
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