Abstract
Rheumatic diseases (RD) and malignancies may be connected to each other in different ways. It has previously been shown, that RD can be a primary manifestation of an underlying cancer as a paraneoplastic syndrome (PNS). RD are related with increased incidence of different malignancies due to the characteristic of the disease or as a result of drug therapy, for instance immunosuppressive agents and tumor necrosis factor inhibitors .
Highlights
Rheumatic diseases (RD) and malignancies may be connected to each other in different ways. It has previously been shown, that RD can be a primary manifestation of an underlying cancer as a paraneoplastic syndrome (PNS)
The PNS may be the patient's primary complaint and occurs up to two. The purpose of this case report is to emphasize the challenging elements in the differential diagnosis within rheumatology, and to describe a newly defined group of very aggressive lymphomas, so-called double-hit lymphoma (DHL), which are characterized by cytogenetic translocation of both MYC and BCL2
Indicates that the cancer is located in two separate regions, an affected lymph node or organ and a second affected area, and that both affected areas are confined to one side of the diaphragm - that is, both are above the diaphragm, or both are below the diaphragm
Summary
Severe joint pain as a manifestation of paraneoplastic rheumatic syndrome in a patient with a malignant lymphoma a case report and review of the literature Asmussen Andreasen, Rikke; Emamifar, Amir; Bang, Jacob Christian; Møller, Michael Boe; Jensen Hansen, Inger Marie. Citation for pulished version (APA): Asmussen Andreasen, R., Emamifar, A., Bang, J. Severe joint pain as a manifestation of paraneoplastic rheumatic syndrome in a patient with a malignant lymphoma: a case report and review of the literature. Terms of use This work is brought to you by the University of Southern Denmark. Unless otherwise specified it has been shared according to the terms for self-archiving. If no other license is stated, these terms apply:
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