Abstract
Background: Hypoglycemia is an acute complication of diabetes especially in elderly patients and a leading cause of emergency room visits and hospital admissions. Several risk factors, such as age, polypharmacy, inadequate food intake, and infections, can further increase the risk of recurrent hypoglycemia and complicate its management. Objective: This report aims to present a case of severe and recurrent hypoglycemia induced by Glibenclamide in an elderly patient with concurrent infection. Case: A 66-year-old female was admitted to the emergency department (ED) in an unconscious state. After a thorough history taking and examination, the patient was diagnosed with profound hypoglycemia induced by sulfonylurea and urinary tract infection. Recurrent episodes of hypoglycemia were observed during treatment despite the administration of Dextrose 40%. Conclusion: Severe hypoglycemia is a common and life-threatening complication. Glibenclamide is a known cause of severe hypoglycemia, although other risk factors may also contribute to its occurrence. Infections can exacerbate hypoglycemic episodes, making them more difficult to manage. Clinicians must remain vigilant about recurrent episodes of hypoglycemia as prompt treatment is associated with a good prognosis
Published Version
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