Abstract
Two new sesquiterpenes, dunnianoside I (1) and 8′-oxo-6-hydroxy-dihydrophaseic acid methyl ester (2), a new glycoside, dunnianoside J (3), two new neolignans, dunnianeolignans A–B (4, 5), together with 10 known compounds (6–15), were isolated from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HR-ESI-MS, and chemical methods. Compounds 7, 8, and 13–15 exhibited potent antioxidant activities against Fe2+-cystine-induced rat liver microsomal lipid peroxidation, with IC50 values ranging from 4.2 ± 0.4 to 38.4 ± 2.6 μM.
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