Antioxidant phenolic glycosides from the roots of Illicium dunnianum

Abstract

Eight new phenolic glycosides, dunnianosides A–H (1–8), and nine known phenolic glycosides (9–17), were isolated from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HRESIMS, and chemical methods. Compounds 1–5, 7, and 9 exhibited potent antioxidant activities against Fe2+-cystine-induced rat liver microsomal lipid peroxidation, with IC50 values ranging from 3.8±0.6 to 23.0±2.2μM.