Serum uric acid is associated with common cardiovascular risk factors in Uygur population

Abstract

Objective: To assess the prevalence of metabolic syndrome in patients with essential hypertension and to explore the inter-relationships between differentmetabolic factors andessential hypertension.Designandmethods: 1517 consecutive patients (811 men) were recruited in the Hypertension Clinic of BangaBandhu Sheikh Mujib Medical University (BSMMU), Dhaka, BangladeshfromApril2000toMarch2003.Metabolicsyndromewasdefined asco-occurrenceofanythreeof the followingtraits: abdominalobesity(waist circumference >102 cm in men and 88 cm in women), abnormal fasting serum level of glucose (≥110mg/dL), triglycerides (≥150mg/dL) and high density lipoprotein cholesterol (≤40mg/dL in men and <50mg/dL in women). Hypertensionwas common to all subjects and defined as the blood pressure≥140/90mmHg or the use antihypertensive medications. Results: All traits were present in 1.1% men and 12.8% women. Combination of different three traits were present as follows; hypertension with high triglyceride and low HDL (men 29.4% vs. women 51.8%), hypertension with highbloodglucoseand lowHDL(men13.5%vs.women29.8%),hypertension with high glucose and high triglyceride (men 18.1% vs. women 18.1%), hypertensionwith high blood glucose and largewaist (men 2.7% vs. women 25.7%), hypertension with high triglyceride and large waist (men 3.4% vs. women39.3%) andhypertensionwith lowHDLand largewaist (men2.5%vs. women70.6%).Conclusion:Thisstudyshowsthat themetabolic syndromeis highly prevalent among hypertensive patients especially women.