Abstract
The purpose of this study was to estimate and compare the levels of tissue non-specific alkaline phosphatase isoenzyme in serum of healthy individual and in chronic periodontitis patients with varying severity. Serum samples were obtained from 31individuals. 10 from healthy individuals and 21 from chronic periodontitis patients categorized as mild, moderate and severe based on CAL values. The samples were used to determine the Tissue Non - Specific Alkaline Phosphatase Isoenzyme (TNSALP) level. Evaluation and comparison of the tissue non - specific alkaline phosphatase isoenzyme activity between the control and chronic periodontitis patient group showed a decrease in bone type of tissue non - specific alkaline phosphatase level among mild, moderate and severe chronic periodontitis patients group. The steady decrease in Bone type of TNSALP might help to provide useful information if monitored successively over a period of time.
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