Abstract
New theories have been advanced in recent years relating to the effect of malnutrition on the serum proteins. During and after the World War, when underfeeding of large portions of the European population was widespread, there resulted a definite clinical condition, the so-called war or Oedemkrankheit, characterized by varying degrees of edema, physical and mental debility and rapid amelioration of symptoms when an adequate diet was supplied. The condition was definitely related by observers, such as Budzynski and Chelchowski, 1 Park 2 and Jansen 3 to dietary deficiency, especially in proteins. On the basis of Kohman's 4 experimental work with the feeding of protein-deficient diets to rats, amplified by Frisch, Mendel and Peters, 5 in which edema and low serum proteins resulted, Peters and his co-workers 6 have postulated the direct effect of malnutrition on the serum proteins and a lowering especially of the serum albumin. They observed edema
Published Version
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