Abstract
Serum proteins were sampled from 318 old field mice, Peromyscus polionotus , collected from 21 sites along a 90-mile transect through central South Carolina. Polymorphisms of transferrin, albumin, prealbumin, postalbumin, and other proteins were demonstrated by electrophoresis. The inheritance of two transferrins C and E was controlled by co-dominant alleles, Trf c , and Trf e . Abnormal segregation ratios involving a third transferrin, D , were observed. Significant differences in the frequency of one allele, Trf e , were observed among the three major areas of the transect, which were separated by river-swamp systems, with the allele apparently being absent at the northeast extreme. Marked variation in frequency of the Trf e allele between neighboring, but semi-isolated, collection sites was interpreted as evidence of founder effect.
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