Abstract

The concentrations of 7 serum proteins have been measured by the technique of single radial immunodiffusion in maternal-cord serum pairs from term pregnancies. Statistical analysis of the data reveals an effect of labor and the mode of delivery on the concentration of several proteins in both maternal and cord sera, which appears different for each macromolecule concentration measured. From the data obtained, IgG, the protein known to cross the placenta, does not appear to be actively transported nor transported against a concentration gradient. The data also suggest that measurement of protein concentration in serum obtained following labor and delivery may not accurately reflect the condition of the fetus in utero.

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