Abstract

Employing the technique of single radial immunodiffusion, the concentrations of 8 serum proteins have been measured in cord serum and amniotic fluid, and compared to the levels in maternal serum and in sera of nonpregnant women. A significant decrease in albumin, IgA, IgM, ceruloplasmin, and transferrin concentration was observed in cord serum. IgG and α1-antitrypsin concentrations were significantly elevated in both maternal and cord serum above the nonpregnant concentration. All 8 proteins were detected in amniotic fluid in low concentration.

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