Abstract
Background: Is to investigate the level of Obestatin in PCOS patients and compare with controls and also see the correlations between the serum Obestatin levels and HOMA-IR.
 Patients and methods: We analyzed 30 patients with PCOS and 20 normal women as controls. PCOS patients were divided into two groups based on obese group and non-obese group Serum Obestatin levels, Insulin Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) determined and compared among both groups.
 Results: Serum Obestatin levels were significantly lower in obese PCOS group than non-obese and control.
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