Abstract
The use of lithium salts and lithium carbonate in particular, in the control and treatment of certain types of psychiatric patients requires a means of monitoring lithium levels in serum. The currently accepted theraputic concentrations cover the range 0.5–1.5 milliequiv-alents of lithium per liter ( mEq l .) of serum with toxic symptoms reported above 1.5–2.0 mEq l . Atomic absorption spectroscopy has been the method of choice for this analysis for several years and with the development of flameless methods the smaller samples may be used and multiple determinations made in about the same time required for a single determination using an air-acetylene flame and aspiration technique. The standard deviation of the flameless method is approximately 5% relative over the range of interest, 0.5–2.0 mEq l . A comparison of results is made using a Perkin-Elmer Model 303 AA unit and a Varian Model AA5 with Model 63 Carbon Rod Atomizer.
Published Version
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