Abstract
<h2>Abstract</h2> Radioimmunoassays for serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and competitive binding assays for serum progesterone were performed upon normal women and in 5 patients during 7 treatment cycles with human menopausal gonadotropin (HMG)/human chorionic gonadotropin (HCG) therapy. The FSH and LH determinations in the patients with induced ovulation differ considerably from those of the normal menstrual cycle and suggest that efforts to mimic a normal menstrual cycle are probably unnecessary in the treatment of anovulatory women. Induced multiple ovulation with resultant multiple corpora lutea produced serum progesterone levels approximately 2 to 3 times those found in normal singleton gestations. Evidence is given for the endogenous trophoblastic elaboration of HCG at approximately Days 8 to 9 of gestation following induced ovulation and for apparent suppression of FSH during the gestational period. Those patients who have higher pretreatment LH levels initially exhibit moderate suppression of serum LH followed by an elevation during the latter half of HMG administration. Those with low initial values do not.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call