Abstract

Exposure to ethinyl estradiol varies with the contraceptive regimen employed, but which contraceptive is the least estrogenic? In this open-label trial, Dutch investigators compared serum EE levels during use of three estrogen-progestin contraceptive methods: the vaginal ring (15 μg EE/120 μg etonogestrel daily), the transdermal patch (20 μg EE/150 μg norelgestromin daily), and an oral contraceptive (OC; 30 …

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