SERUM CALCIUM LEVEL AND THE ASSOCIATED FACTORS ON REGULAR HEMODIALYSIS PATIENTS

Abstract

Chronic kidney disease-mineral bone disorder (CKD-MBD) is a chronic complication of regular hemodialysis (HD) patients. Previously, several study had found that serum calcium in regular hemodialysis patients can be low, normal or high level. However, there is a lack of data in our region. This study is a cross-sectional descriptive analytic study to obtain serum calcium level and the associated factors. Serum calcium were measured by calorimetric methods using Arsenazo III then it was classified into low, normal, and high serum calcium level according to Indonesian Society of Nephrology consensus. This study collected 100 patients who perfomed chronic hemodialysis at Sanjiwani Gianyar and Ari Canti hospital which consisted of male (67%) and female (33%). The mean age was 52.52 years with 44.6 months of mean dialysis vintage. Most of the subjects underwent hemodialysis twice a week (96 %) with total HD duration of 9 hours a week. Sixty six percent of the subjects used arterio-venous fistula for vascular access. This study showed that most chronic hemodialysis patients (60%) had low serum calcium level (<8.4 mg/dL). Linier regression test indicated that serum calcium is significantly influenced by serum phosphate, however, serum urea has less powerful effect to serum calcium concentration with r = -0.371 and r= -0.013 respectively with r2= 0.313. This study obtained that most of the subjects had low serum calcium level and the serum calcium associated with serum phosphate and serum urea. Keywords: CKD-MBD; Hemodialysis; Serum Calcium.