SEROPREVALANCE OF TRANSFUSION TRANSMITTED INFECTIONS AMONGST BLOOD DONORS IN TERTIARY CARE HOSPITAL IN U.P

Abstract

Background: The evaluation of the data of the prevalence of transfusion transmissible infections (TTI) among blood donors permits an assessment of the acquisition of the infections in the blood donor population and consequently safety of the collected donations. It gives an idea for the epidemiology of these infections in the population. Objectives: To study seroprevalence of HIV,HBV,HCV,Syphilis and malaria in blood donors. Methods:Total of 4529 units of blood were collected from voluntary and replacement donors during three years study period from Jan 2019 to dec 2021. All the blood samples were screened for HIV,HbsAg,HCV,Syphilis and malarial parasites. Results: Out of the total 4529 blood donors, replacement donors were (79.50%) more compared to voluntary donors (20.40%).The overall seroprevalence of TTI was 4.10%.The seroprevalence of HIV,HbsAg and HCV was 0.04%,1.81% and 2.16% in total donors respectively. No voluntary donor was found to be positive for HIV. The prevalence for HbsAg and HCV was more in replacement donors 1.67% and 2.03% respectively as compared to voluntary donors 0.14% and 0.13% respectively.No donors were found positive for Syphilis and Malaria. Conclusion: Replacement donors were found to be more seropositive for TTI as compared to voluntary donors.Hence,more attention should be given for motivation of voluntary donors