Serological study of human Cytomegalovirus spread among aborted women in Najaf Governorate and assessment of MCP-1 chemokine effect on the virus

Abstract

This study aims to determine the prevalence of IgM, IgG, anti-Human cytomegalovirus (HCMV) in Najaf women and determining the level of MCP-1 chemokine concentration and its role in the immune response. This study was conducted on 65 were suffering from HCMV infection and were referred to the women's consulting clinic and maternity halls in each of the Al-Zahra teaching hospital and Al-Manathira general hospital and 15 women as a control without any miscarriage, during the period from 6 April to 12 June, and these samples were chosen within the age range is between (18 to 40) years. HCMV IgM, IgG antibody tests were performed using Enzyme-Linked Immunosorbent Assay, and the result showed that the prevalence of IgG and IgM immunoglobulins in pregnant women with miscarriages according to the statistical analysis that there is a high significantly difference with a level ≤ P 0.05 in IgG and IgM concentration within different age groups of aborted women compared to the control treatment group of women.