Abstract
To the Editor: Anti-p200 pemphigoid is an autoimmune blistering disease characterized by circulating autoantibodies binding to the dermal side of human salt-split skin (SSS) by indirect immunofluorescence (IIF) microscopy and reactivity against a 200-kDa protein in the extract of human dermis by immunoblotting (IB).1 Laminin γ1 has been identified as a major target antigen and can be detected in about 90% of sera.2 This retrospective single-center study included all 245 anti-p200 pemphigoid sera analyzed between 2008 and 2017 in our routine autoimmune laboratory with a compatible clinical picture and reactivity with the p200 protein.
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