Abstract
Tamoxifen is an anti estrogen recommended in the treatment of estrogendé pendants cancers. Its side effects are rare and haematological toxicity is extremely rare. We relate an original case of severe erysipelas which revealed a toxic myelopathy to tamoxifen.
Highlights
Tamoxifen is an anti estrogen recommended in the treatment of estrogen-dependent cancers
We present an original case since it is the first that brings a deep bicytopenia to tamoxifen, with its diagnostic and therapeutic difficulties
Bone marrow biopsy objectified bone marrow hyperplasia with signs of dysmyelopoiesis, PRCA and densification of the reticulin network can be compared with a toxic myelopathy (Figure 3)
Summary
Tamoxifen is an anti estrogen recommended in the treatment of estrogen-dependent cancers. Its side effects are rare and its haematological toxicity is extremely rare. We present an original case since it is the first that brings a deep bicytopenia to tamoxifen, with its diagnostic and therapeutic difficulties.
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