Abstract

Background and Aims : seq−1 peptide (CHLLVDFLQSLS) derived from the C-terminus segment of the cholesteryl-ester transfer protein (CETP), corresponds to the active component of therapeutic nasal vaccine HB-ATV-8, designed to prevent and control the processes of atherosclerosis and fatty liver disease. During our investigation, we have previously established in vivo (rabbit and pig models), the protective effect of vaccine HB- ATV-8 against the development of these two diseases.

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