Abstract
This paper describes further studies of the separation of amino acid racemates on chemically bonded chiral phases by ligand exchange chromatography. The stationary phase consists of a silica support to which l-amino acids as chiral components are bonded via 3-glycidoxypropyltrimethoxysilane. Important factors affecting the selectivity and efficiency of the separations are the pH and ionic strength of the mobile phase, as well as the temperature. Examples for the separation of mixtures of racemic amino acids are given.
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