Abstract
Background: Infection with Candida species has been increased globally during the past decade. This can be due to the increase in the number of patients with immunodeficiency problems like cancer, HIV AIDs, organ transplantation and hospitalization in ICUs. We aimed to investigate the prevalence rate of the fungal colonization and related species in chemotherapy-subjected children with malignancy. Methods: Present analytical-applied research was conducted on 128 chemotherapy-subjected children with malignancy. Blood and urine samples were collected from all the patients; afterwards, the urine samples were cultivated on Saborrads Dextrose Agar and the blood samples in ordinary culture bottles (monophasic culture method and blood culturing). Then, the developed fungi were separated from the culture medium and subjected to identification tests. Results: There was no significant relationship between the age group and infection with fungus (P=0.998) but there was a significant relationship between gender and fungus infection (P=0.049) in such a way that fungus infection was found more prevalent amongst the females. Overall, 28 individuals (58.33%) were found infected with C. albicans; 9 (18.75%) with C. tropicalis; 5 (10.42%) with C. glabrata; 3 (6.25%) with C. kefir; 2 (4.116%) with C. krusei and 1 (2.09%) with C. parapsilosis. Conclusion: C. albicans is the most common species in this geographical area. The best treatment for these infectious diseases is voriconazole.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call