Abstract

ZIF-8 is a typical metal–organic framework (MOF) material, which has great potential for sensor improvement. In this paper, we prepared a high sensitivity surface plasmon resonance (SPR) sensor based on ZIF-8/Au and described the preparation process of the sensor and characterized the samples in detail. The results showed that the synthesized ZIF-8 nanoparticles were uniform with an average diameter of about 50 nm. The performance of the sensor was related to the amount of ZIF-8, which could be controlled by adjusting the number of spin-coating cycles. When the refractive index ranged from 1.3335 to 1.3635, the maximum sensitivity of the sensor reached 3961.36nm/RIU with one cycle of spin-coating, which was 74.05% higher than that of pure Au single-layer film sensor. Furthermore, the feasibility of the proposed sensor for biological sensing was demonstrated by detecting bovine serum albumin (BSA).

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