Sensitive Electrochemical Determination of Baicalein Based on D‐Ti3C2Tx MXene/Fullerene Composite Modified Glassy Carbon Electrode

Abstract

AbstractIn this work, an electrochemical sensor was developed based on the delaminated titanium carbide nanosheet (d‐Ti3C2Tx) and fullerene (C60) composite modified glassy carbon electrode (GCE). The composite materials d‐Ti3C2Tx/C60 were characterized by scanning electron microscopy (SEM), X‐ray diffraction (XRD), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The prepared modified electrode (d‐Ti3C2Tx/C60/GCE) exhibited commendable electrocatalytic activity for the oxidation of baicalein. Under the optimum detection conditions, the detection of baicalin showed a wide linear range of 0.015–4.0 μM with a detection limit of 0.005 μM. In addition, the d‐Ti3C2Tx/C60/GCE showed good reproducibility, stability and anti‐interference. It was also successfully used for the determination of baicalin in the commercially available Shuanghuanglian oral liquid with satisfactory results.