Sensitive and high recovery electrochemical sensing of resorcinol by Cd–glutathione complex-modified glassy carbon electrode

Abstract

ABSTRACT Resorcinol belongs to class of phenolic compounds with high medicinal importance due to antiseptic and disinfectant properties. In this research, cadmium–glutathione (Cd–GSH) complex has been synthesised by single sept strategy and used for electrochemical sensing of resorcinol. Synthesised complex is characterised by UV/Visible spectrophotometer, Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). Cyclic voltammetry (CV), with three-electrode system, is used for sensing of resorcinol. Cd–GSH-modified glassy carbon electrode (GCE) shows redox response for resorcinol and parameters including pH, concentration and scan rate are optimised. Results indicate that peak current of resorcinol is the highest in PBS buffer solution of pH 7.4. Under optimised experimental conditions, the anodic peak current of resorcinol shows linear trend (R2) in the range of 0.996 and limit of detection (LOD) up to 0.3 μM by amperometry, which is significantly higher than some other reported materials. Observed recovery of resorcinol from tap water (113%) and pond water (138%) also justified by Cd–GSH complex-modified electrode. Furthermore, synthesised complex is selective for resorcinol in the presence of higher concentrations of ascorbic acid and uric acid. Good stability and reproducibility up to 30 cycles indicate the potential use of complex as electrochemical sensors.