Abstract
Objective: To study the effect of organic solvents on male semen quality among the shoe manufacturing industrial workers.
Highlights
Occupational exposure to toxic agents is one of the most prevalent occupational and environmental health problems in the world today
Conclusion(s): The results suggest that the organic solvents could affect the semen quality of the workers in terms of sperm morphology which might be considered as one of the reason for abnormal pregnancies among the wives of the workers
Epidemiological studies have revealed that the occupational exposure to toxic agent leads to reproductive toxicity such as poor semen quality [1] and male mediated adverse pregnancy outcomes such as spontaneous abortions, congenital malformations and premature births [2,3]
Summary
Occupational exposure to toxic agents is one of the most prevalent occupational and environmental health problems in the world today. Organic solvent is an important occupational health problem due to its wide spread usage in industries like shoe making, spray painting and paint manufacturing. There are certain operations where organic solvent exposure is significant and constitute a health hazard to the workers in shoe manufacturers. These operations are mainly waxing, gluing and polishing [4,5]. Exposure to organic solvents in shoe factories has been reported to increase the risk for acute and chronic health problems [6]. Higher incidences of cancer are reported in subjects exposed to solvents characterized by its reactive metabolites which are presumed to induce oxidative damage on vital organs and to the hematopoietic system [7]
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