Selenium concentrations in the blood and urine of a healthy Polish sub-population.

Abstract

Selenium (Se) levels in whole blood, red blood cells, and plasma taken from 199 healthy subjects were investigated and found to be 101.1 micrograms/1 (whole blood), 133.1 micrograms/1 (packed red blood cells), and 78.0 micrograms/1 (plasma). In 62 samples of urine, the selenium level, expressed as micrograms/g creatinine, was 11.4. The mean whole blood selenium concentration was significantly higher in men than women: 104.5 +/- 23.2 vs. 96.9 +/- 21.2 micrograms/1. No differences were found in red blood cells, plasma and urine between male and female subjects. A strong linear correlation was observed between red blood cell and whole blood selenium levels (r = 0.879; p less than 0.001) as well as between selenium levels in whole blood and plasma (r = 0.806; p less than 0.001). A weaker but still significant linear correlation was found between urine and whole blood as well as between urine and plasma selenium concentrations. The relatively low levels of the element in the blood and urine are probably due to its deficiency in the diet.