Abstract
Homolytic hydroxyalkylation of quinoline derivatives by redox systems is described. The direct introduction of hydroxyalkyl groups into heteroaromatic ring of quinoline derivatives has been achieved by means of hydrogen peroxide. The good yields and the complete selectivity obtained are due to the nucleophilic character at heteroaromatic ring of the hydroxyalkyl radicals. It is useful to apply this reaction to other synthetic reactions.
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