Abstract
1. 1. The author's experiences with crystallinetrypsin tryptar) has been briefly reviewed. 2. 2. Chymotrypsin and trypsin together in equal enzyme strength exhibit potentiated proteolysis-more than 200 per cent more rapid than an equal concentration of trypsin alone. 3. 3. Chymotrypsin is relatively non-toxic, does not delay healing or alter the microscopically visible course of events when applied to open wounds. 4. 4. A number of illustrative cases show the adequacy of the new enzyme system of trypsin and chymotrypsin in handling fibrinopurulent necrotic lesions which have failed to respond to the usual surgical measures. 5. 5. The combination of trypsin and chymotrypsin in equal enzyme strength when properly applied to the fibrinopurulent necrotic lesion which has failed to respond adequately to the usual surgical measures, rapidly eliminates noxious elements which prevent healing. In the presurgical preparation of the lesion in which tissue salvage is imperative this new enzyme system offers a safe, effective means of eliminating all necrotic detritus, leaving the healthy viable tissue intact and unaltered. Herein lies the uniqueness of this physiologic enzymatic cleansing process: it automatically halts its dkbridement at the fine line between life and death.
Published Version
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