Selection of coherence transfer pathways by pulsed‐field gradients in nmr spectroscopy

Abstract

AbstractThe use of pulsed‐field gradients has emerged as a promising approach for the selection of coherence transfer pathways in NMR spectroscopy. Applying field gradient pulses instead of phase cycling can reduce data acquisition time, minimize artifacts, and provide new ways to suppress solvent signals. This paper provides a practical introduction to the technique. The selection of coherence transfer pathways by field gradient pulses is based on the characteristic sensitivities of coherence to field gradients and on the formation of coherence transfer echoes. A general formulation for selection of coherence transfer pathways by field gradient pulses is provided. Examples are used to illustrate the design of field gradient pulse sequences for the selection of specific coherence transfer pathways in multiple‐pulse experiments.