Abstract

To evaluate the role of sediment cytology of biopsy specimen fixatives in early diagnosis of oral neoplasms. Cytological smears were prepared by centrifuging the fixatives in which the biopsy specimens were received. The smears were analyzed and the cytological results were compared with histological diagnosis. Of 20 lesions studied by sediment cytology, 8 were labeled as benign, 9 as malignant and 3 cases as inconclusive. Final histopathological diagnosis labeled 12 lesions as malignant and 8 lesions as benign. Comparing the cytological diagnosis with histological sections, 17 out of 20 cases were concordant. The overall diagnostic accuracy of 85% was achieved. Biopsy sediment cytology is a good complimentary method to histopathology in the study of oral biopsy material.

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