Abstract

Objective To evaluate the applicability of bispectral index (BIS) in assessing sedation in pediatric intensive care unit. Methods Patients in pediatric ICU,aged six months to thirteen years and requi-ring sedation were given midazolam as sedative drug. The Ramsay score was assessed by physicians after mi-dazolam was given at ten time interval and these data were compared with the blinded BIS score. Results A total of 42 children were included in the study,420 valid paired observation of BIS values and Ramsay score were performed. According to Spearman's scale analysis, the correlation coefficient between BIS value and Ramsay score was -0.887 9 (P 0.05). Conclusion BIS values cor-relate fairly well with the Ramsay scores in PICU patient. With the advantages such as simpleness, time-sav-ing,continuity and etc,BIS monitoring is a good objective tool for judging sedation depth of PICU patients. Key words: Bispectral index; Ramsay Score; Midazolam

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