Abstract

A Heidenhain pouch usable for several months was constructed in a Landrace secondary SPF piglet. The behaviors of electrolytes and pepsin in the gastric juice induced by tetragastrin (TG) were studied in the piglet, in comparison with the dog. A high positive correlation was observed between H+ concentration and secretory volume. The same results were obtained by stimulation with betazole and carbamylcholine. The concentrations of Na+ and Ca++ decreased, but those of K+ and Cl- increased with an increase in volume. The concentrations of these 4 ions correlated highly with H+ concentration or volume. Mg++ concentration increased temporarily after the TG administration and decreased there after. This curious responste of Mg++ concentration was observed in the dog, as well as in the piglet, after administration with any other stimulant. Pepsin concentration increased temporarily after TG stimulation, then turned to be at a basal level, and increased slightly thereafter. The kinetics of electrolytes on the gastric juice in the pig seemed to resemble that in the dog.

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