Abstract

Further studies have been carried out on the nature and the behaviour of the anti-SRC plaque-forming cells from the adherent fraction of mouse spleen cells. In this fraction many phagocytic, acid phosphatase-positive cells were observed in the center of the plaques. The glass-adherent PFC were found to be highly radioresistant in vitro, compared to the nonadherent fraction. In both primary and secondary immune responses, only the direct PFC showed the tendency to adhere to glass. The phenomenon of the glass adherence of a fraction of direct PFC is also apparent in mouse spleen cells stimulated in vitro with SRC.

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