Abstract

<p indent="0mm">Gastric cancer (GC) is a major public health problem threatening China’s health system. Hence, diagnosis and effective intervention for people at high risk of GC are crucial for the secondary prevention of GC. It is critical to prevent and treat GC by systematic analysis of the pathological transformation mechanism of the precancerous lesions of GC (PLGC), establish a perfect high-risk evaluation and diagnostic system for GC, and develop a safe and effective treatment. As the treasure of Chinese culture, traditional Chinese medicine (TCM) demonstrates the characteristics and advantages in the treatment of complex system diseases. It is worth noting how to systematically explain the evolution rule of the combination of diseases and TCM syndromes in every pathological state of the PLGC, objectively evaluate the advantages of clinical efficacy of the intervention, and comprehensively analyze the mechanism and material basis of the effectiveness of TCM, which will play a better role in improving the efficiency of the secondary prevention system of GC with TCM and Western Medicine cooperation. Here, we systematically review the important role of TCM in the prevention and control of GC in China and the necessity and feasibility of establishing a secondary prevention system for GC in China. Finally, in order to provide constructive opinions and suggestions for the establishment of the secondary prevention and treatment system of GC with a collaboration between TCM and Western medicine, several perspectives were provided on building a collaborative platform of TCM and Western medicine, jointly carrying out evidence-based and basic research on the treatment of PLGC with TCM.

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