Abstract
BackgroundPrevious reports have described hypogonadism associated with virus infection such as hantavirus, human immunodeficiency virus (HIV) or severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). However, to our best knowledge there has been no case report of secondary hypogonadism following hand, foot, and mouth disease (HFMD).Case presentationA previously healthy 28-year-old man with no history of major physical and psychological trauma, presented with bilateral gynecomastia and erectile dysfunction 2 weeks after HFMD. Laboratory testament showed the level of gonadotropin hormones declined. Imaging examination demonstrated no major abnormal change in pituitary or reproductive system. The diagnosis of hypogonadism was established. Then the patient was ordered to maintain mental health outward of hospital without drug intervention. One month after presentation, his gonadotropin hormone level and sexual desire had recovered, while bilateral gynecomastia and erectile dysfunction symptoms disappeared.ConclusionsPhysicians should notice the possibility for hypogonadism in adult patients with a recent history of HFMD.
Highlights
Previous reports have described hypogonadism associated with virus infection such as hantavirus, human immunodeficiency virus (HIV) or severe acute respiratory syndrome coronavirus 2 (SARS-COV-2)
Physicians should notice the possibility for hypogonadism in adult patients with a recent history of HFMD
*Correspondence: 18678991617@163.com 1 Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao 266003, China Full list of author information is available at the end of the article especially those living with infected children, may suffer from HFMD
Summary
Previous reports have described hypogonadism associated with virus infection such as hantavirus, human immunodeficiency virus (HIV) or severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). Conclusions: Physicians should notice the possibility for hypogonadism in adult patients with a recent history of HFMD. *Correspondence: 18678991617@163.com 1 Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao 266003, China Full list of author information is available at the end of the article especially those living with infected children, may suffer from HFMD.
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