Abstract

Profound inspection of the life forms on the earth teaches how to be the complexity of interrelationships among the various systems. Because of the emergence of novel viruses all the time and the inadequate of vaccines and antivirals, viral contagions are amongst the most causative diseases affecting people worldwide. Fungi exemplify a massive source of bioactive molecules as, many fungal secondary metabolities like Oxoglyantrypine, Carneic acid F, Scedapin C, Asteltoxin E, Phomanolide, Norquinadoline A and Quinadoline B have antiviral activity. This review deals with how secondary metabolites of fungi can help in the war against viruses in general and especially Coronaviruses moreover several pieces of literature pointed out that many clusters of fungi in different biotopes are waiting to be exploited.

Highlights

  • Difficulties arise, when attempts are made to deal with viruses, because of the unique structural system, which does not react to the ordinary drugs such as the ordinary antibiotics that cannot treat viral infections, most viral illnesses could be managed by the immune system and can effectively heal the illness within 7 to 10 days (Murphy et al, 2012)

  • The findings indicate that 90% of naturally occurring antibiotics and compounds including fungal secondary metabolites (FSMs) may possess antiviral capabilities (Linnakoski et al, 2018), because of that the FSMs may be a gifted option

  • Depending on the viral construction, SARS-CoV-2 is an enveloped virus, this feature can facilitate the antiviral activity of the FSMs

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Summary

Introduction

Biological sciences have accomplished enormous discoveries in numerous arenas. Microorganisms are one of them, despite this, viruses as unique creatures, still have several aspects to be discovered. Difficulties arise, when attempts are made to deal with viruses, because of the unique structural system, which does not react to the ordinary drugs (used to manage bacterial and fungal diseases) such as the ordinary antibiotics that cannot treat viral infections, most viral illnesses could be managed by the immune system and can effectively heal the illness within 7 to 10 days (Murphy et al, 2012).

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