Abstract

In our study, we added a three-dimensional automated breast ultrasound (3D ABUS) to mammography to evaluate the performance and cancer detection rate of mammography alone or with the addition of 3D prone ABUS in women with dense breasts. Our prospective observational study was based on the screening of 1165 asymptomatic women with dense breasts who selected independent of risk factors. The results evaluated include the cancers detected between June 2017 and February 2019, and all surveys were subjected to a double reading. Mammography detected four cancers, while mammography combined with a prone Sofia system (3D ABUS) doubled the detection rate, with eight instances of cancer being found. The diagnostic yield difference was 3.4 per 1000. Mammography alone was subjected to a recall rate of 14.5 for 1000 women, while mammography combined with 3D prone ABUS resulted in a recall rate of 26.6 per 1000 women. We also observed an additional 12.1 recalls per 1000 women screened. Integrating full-field digital mammography (FFDM) with 3D prone ABUS in women with high breast density increases and improves breast cancer detection rates in a significant manner, including small and invasive cancers, and it has a tolerable impact on recall rate. Moreover, 3D prone ABUS performance results are comparable with the performance results of the supine 3D ABUS system.

Highlights

  • Introduction iationsNumerous studies have proven that, in the last 30 years, cancer mortality has decreased; this is predominantly due to an increase in mammography screening programs.Given the diminishing number of late-stage cancers, it should be clear that mortality has diminished, with statistics reporting a 45% decrease in death rates [1]

  • Twelve women were diagnosed with breast cancer, including four cancers detected with mammography alone, while another eight cancers were detected by adding 3D prone three dimensional automated breast ultrasound system (ABUS) (Figure 2, Table 2)

  • Our study shows a high sensitivity of the prone ABUS system associated with mammography (93.5%). which is comparable to the sensitivity found in the more famous

Read more

Summary

Introduction

Numerous studies have proven that, in the last 30 years, cancer mortality has decreased; this is predominantly due to an increase in mammography screening programs. Given the diminishing number of late-stage cancers, it should be clear that mortality has diminished, with statistics reporting a 45% decrease in death rates [1]. Progress in recognizing genetic markers and risk causes for cancer notwithstanding, about 70/80%. The main plan of action for decreasing and reducing cancer mortality by increasing early detection remains the screening program. Standard mammography breast cancer screening has helped to reduce breast cancer mortality [4]. The number of cancers not detected during a mammogram is substantial, especially when it comes to women with dense breasts, with a sensitivity

Objectives
Methods
Results
Discussion
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call