Abstract
The time it takes for a completed manuscript to be published traditionally can be extremely lengthy. Article publication delay, which occurs in part due to constraints associated with peer review, can prevent the timely dissemination of critical and actionable data associated with new information on rare diseases or developing health concerns such as Zika virus. Preprint servers are open access online repositories housing preprint research articles that enable authors (1) to make their research immediately and freely available and (2) to receive commentary and peer review prior to journal submission. There is a growing movement of preprint advocates aiming to change the current journal publication and peer review system, proposing that preprints catalyze biomedical discovery, support career advancement, and improve scientific communication. While the number of articles submitted to and hosted by preprint servers are gradually increasing, there has been no simple way to identify biomedical research published in a preprint format, as they are not typically indexed and are only discoverable by directly searching the specific preprint server websites. To address this issue, we created a search engine that quickly compiles preprints from disparate host repositories and provides a one-stop search solution. Additionally, we developed a web application that bolsters the discovery of preprints by enabling each and every word or phrase appearing on any web site to be integrated with articles from preprint servers. This tool, search.bioPreprint, is publicly available at http://www.hsls.pitt.edu/resources/preprint.
Highlights
Preprint servers are online repositories that manage access to manuscripts that have not yet been peer-reviewed or formally published in a traditional manner
Many avid Google Scholar (GS) users try a workaround by including preprint with the query term, (E.g., “asthma preprint” or “CRISPR preprint”) with the assumption of retrieving only preprint articles fetched from major preprint servers
There is a developing movement of preprint advocates who propose that preprints play a role in “catalyzing scientific discovery, facilitating career advancement, and improving the culture of communication within the biology community”[1]
Summary
Preprint servers are online repositories that manage access to manuscripts that have not yet been peer-reviewed or formally published in a traditional manner. To continue to try and gauge the usage of Kallisto in RNA-seq data analysis, the researcher might take an alternative approach: instead of searching PubMed, try searching for preprint articles This can be achieved with a single click of the bioPreprint-bookmarklet once it is installed in the researcher’s web browser. The bioPreprint search engine and bookmarklet can quickly satisfy the student’s curiosity by providing easy access to GTEx-related articles hosted by various preprint servers that may or may not be published “in print” yet This process is simple, unique, and the student doesn’t even need to leave the current web page to go on a literature hunt. The result is sixty-seven articles showcasing the use of GTEx data in a variety of research topics including “Genome Wide Association Studies,” “Allele, Specific expression,” “Expression Quantitative Trait Loci,” etc (searched on 2 May 2016)
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