Abstract

During a scrub typhus outbreak investigation in Thailand, 4 isolates of O. tsutsugamushi were obtained and established in culture. Phylogenetic analysis based on the 56-kDa type-specific antigen gene demonstrated that the isolates fell into 4 genetic clusters, 3 of which had been previously reported and 1 that represents a new genotype.

Highlights

  • During a scrub typhus outbreak investigation in Thailand, 4 isolates of O. tsutsugamushi were obtained and established in culture

  • Compared with the other animals, a higher percentage (100%) of B. indica rats had O. tsutsugamushi infections, indicating that this species might serve as a reservoir host for the bacterium (Table 1)

  • O. tsutsugamushi obtained from the infected children and small mammals was characterized on the basis of Orientia spp.–specific 56-kDa gene fragments

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Summary

Introduction

During a scrub typhus outbreak investigation in Thailand, 4 isolates of O. tsutsugamushi were obtained and established in culture. Author affiliations: Armed Forces Research Institute of Medical Science, Bangkok, Thailand To better characterize the specific strain(s) of O. tsutsugamushi present in the area and to determine how the agent(s) is transmitted to humans, we genetically typed O. tsutsugamushi obtained from these 26 children and small mammals.

Results
Conclusion

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