Abstract
The research was aimed as screening of phytoconstituents and antibacterial effects of Leaf & Stem of Ailanthus excelsa against E. Coli, S. Aureus, A. Niger & A. Flavus. The plants were collected from Bareilly region, Uttar Pradesh and authentication was done by CIMAP, Lucknow. The collected plant material was dried in shade and ground in the grounder. The dried powdered drug material was extracted by 9 different solvents by cold maceration for 12 hrs at room temperature. Mayer’s, Hager’s tests, Fehling’s Wager’s and Molisch test were used for detection of alkaloids, glycosides, saponins, terpenoids etc. After the extraction was complete, it was tested against various species such as E. coli, S. aureus, S. niger and A. Flavus for its antimicrobial potential. The results indicate that methanolic extract showed highest level of phytoconstituents such as alkaloids, glucosides, saponins, terpenoids, flavonoids, and carbohydrates. Extract showed significant antibacterial potential against all the species tested with. In conclusion, this research suggests, that novel molecules should be identified and isolated responsible for specific pharmacological activity.
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