Abstract
Screening of endoscopic microerosions in non-erosive esophagitis by high-definition digestive endoscopy coupled with narrow-band imaging and microerosions analysis by immunohistochemical, pHmetric and histology
Highlights
Gastroesophageal reflux disease (GERD) is considered one of the most prevalent digestive diseases in Western countries
No difference occurred between the groups of participants with typical symptoms of GERD and with or without esophageal microerosions screened by high-definition digestive endoscopy coupled with narrow band imaging (NBI) regarding pHmetric, histological and immunohistochemical analysis
In our study we focused the attention on participants with typical symptoms of GERD and we used high-definition digestive endoscopy coupled with narrow band imaging (NBI) to identify esophageal microerosion
Summary
Gastroesophageal reflux disease (GERD) is considered one of the most prevalent digestive diseases in Western countries. The GERD diagnosis is made through the referred symptoms, associated with diagnostic tests such as upper gastrointestinal endoscopy (UGE), ambulatory monitoring of prolonged pHmetry or impedance-pH monitoring, and clinical response to antisecretory therapy [3,4,5]. Regarding to GERD is recommended the use of the LAC in the endoscopic assessment in patients with erosive esophagitis. The Lyon consensus established standardization in the conduct of the diagnosis of GERD, proposing that only patients with LAC grade C and D, Barrett's esophagus and peptic stenosis would present confirmatory evidence of GERD, and that with LAC grade B the initial drug treatment with proton pump inhibitors would be recommended, but the need for diagnostic complementation for GERD through pHmetry should be highlighted if surgical treatment was need [9].
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