Screening of Chloroform and Methanolic Bark Extracts of Commiphora caudata for its In-vitro Anti-bacterial, Anti-fungal and In-vivo Anti-inflammatory Activity

Raju H V,Nisha S Shirkoli,Shailendra S Suryawanshi,Prasanna S Sutar,Kishori P Sutar

doi:10.47552/ijam.v12i4.2205

Abstract

Herbal medicines and their preparations have been widely used from the thousands of years in developing and developed countries in the primary health care of society and community. They have great demand due its safety, efficacy with minimum side or adverse effects. Commiphora caudata. It’s known as konda mava in kannada, ikkata in Sanskrit and hill mango in English. It’s widely used in the management of various disorders. Hence the identification of bioactive fractions from various parts of selected medicinal plant is important. In the present research work an attempt has been made to screen and assess the antibacterial, antifungal and anti-inflammatory activities of Commiphora caudata barks. The barks of selected plant material were collected, authenticated, powdered and subjected for extraction procedure. The extracts were screened for presence of various phytoconstituents. The antibacterial activity of chloroform and methanolic extracts were performed against various strains of bacteria and fungi. The extracts also were investigated for its in-vivo anti-inflammatory activity. The result of investigation concludes that chloroform and methanolic extract of plant were potential to inhibit the growth of selected strains of microorganism and also produced potential anti-inflammatory effect.

Highlights

Commiphora caudata belongs to the family of Burseraceae belongs to genus Commiphora
Herbal medicines and their preparations have been widely used from the thousands of years in developing and developed countries in the primary health care of society and community
Anti-bacterial activity The antibacterial activity of the extracts was studied in different concentrations on eight pathogenic bacterial strains, Bacillus subtilis, Escherichia coli, Bacillus pumilis, Pseudomonas aeruginosa, Bacillus cerus, Pseudomonas vulgaris, Staphylococcus aureus and Serratia marcens and three pathogenic fungi Aspergillus Niger, Saccharomyces cereviceae, and Penicillin chrysozenum

Summary

Introduction

Commiphora caudata belongs to the family of Burseraceae belongs to genus Commiphora. It’s known as konda mava in kannada, ikkata in Sanskrit and hill mango in English [1]. It is estimated that about 50,000-70,000 plant species are used in traditional and

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