Abstract
The antimicrobial activity of the chloroform extracts of ten marine sponges collected from the Atlantic coast of Morocco and from the Gulf of Thailand was tested against four bacterial species and five fungal species using the agar disk method. Extracts tested showed antimicrobial activity against at least one of the test strains, 50% of them showed antibacterial activity while only 20% exhibited antifungal activity. Among them, the extracts of Hippospongia communis and Ircinia variabilis collected from the Atlantic coast of Morocco appeared to be quite promising due to their capacity to inhibit the growth of Candida tropicalis R 2 (an amphotericin B and nystatin resistant strain) as well as their broad spectrum activity against other bacteria and fungi. The antifungal activity of the extracts was further characterized by determining the minimum inhibitory concentration (MIC) against four fungal species selected using the broth microdilution method and two test media.
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